One of the dogs on trial (left) going camping with his friend.
Pet Dog Monepantel Trial: Participating Clinics and Inclusion/Exclusion Criteria
The monepantel (MPL) treatment naive B cell lymphoma clinical trial program is transitioning from Phase 2 to Phase 3. Finalisation of dosing optimisation is underway, including investigating MPL in combination either with prednisolone or CHOP-based protocols[1]. The trial involves treatment at home with a consultation at the dog’s nearest trial centre, as listed below. Basic Inclusion and Exclusion criteria are also listed below. Trial centre veterinarians will provide greater detail about enrolment and the nature of the trial.
[1] L- asparaginase, vincristine, cyclophosphamide, prednisolone, and doxorubicin
Participating MPL Trial Centres in Australia
Dr Sonya Yu
Animal Referral Hospital,
Homebush, Sydney NSW
tel: (02) 9758 8666
Animal Referral Hospital,
Homebush, Sydney NSW
tel: (02) 9758 8666
Dr Kathleen O’Connell
Animal Referral Hospital,
Sinnamon Park, Brisbane QLD
Tel: (07) 3172 0593
Dr Catherine Chan
Veterinary Specialist Services,
Jindalee, Brisbane, Qld
Tel: 1800 442 648
Dr Sue Bennett
Western Australian Veterinary Emergency and Specialty (WAVES),
Success, Perth WA
Tel: (08) 9412 5700
Dr Jessica Finlay
Perth Veterinary Specialists,
Osborne Park, Perth WA
Tel: (08) 9204 0400
Participating MPL Trial Centres in New Zealand
Dr Tommy Fluen and Dr Mike Coleman
Veterinary Specialists Auckland (VSA)
Sylvia Park Hospital
Corner Hotunui Drive & Te Apunga Place,
Sylvia Park
Auckland
New Zealand
Veterinary Specialists Auckland (VSA)
Sylvia Park Hospital
Corner Hotunui Drive & Te Apunga Place,
Sylvia Park
Auckland
New Zealand
tel: +64 9-320 5645
Participating MPL Trial Centres in the USA
Dr Meighan Daly
Heart of Texas Veterinary Specialty Centre
Heart of Texas Veterinary Specialty Centre
115 E Old Settlers Blvd
Round Rock
TX 78664
USA
tel: +1 512-744-4644
Veterinary Trial Testimonials
To read the pet owners’ trial testimonials, visit www.pharmaust.com/veterinary-trial-testimonials/
Basics of Inclusion Criteria
• Dogs of any sex, at least one year of age, with B cell nodal lymphoma
• No other significant intercurrent disease
• No previous medication for the lymphoma
• WHO stage 1-5, substage a.
• Modified Karnofsky performance score 0 or 1
• No other significant intercurrent disease
• No previous medication for the lymphoma
• WHO stage 1-5, substage a.
• Modified Karnofsky performance score 0 or 1
Basics of Exclusion Criteria
• Dogs that have received prior treatment for lymphoma
• Any corticosteroid use in preceding 8 weeks
• Puppies less than 1 year old
• Lactating or pregnant bitches
• Dogs used for breeding
• Modified Karnofsky performance score 2 or above
• Any corticosteroid use in preceding 8 weeks
• Puppies less than 1 year old
• Lactating or pregnant bitches
• Dogs used for breeding
• Modified Karnofsky performance score 2 or above

[1] L- asparaginase, vincristine, cyclophosphamide, prednisolone, and doxorubicin