Pet Dog Monepantel Trial: Participating Clinics and Inclusion/Exclusion Criteria

The monepantel (MPL) treatment naive B cell lymphoma clinical trial program is transitioning from Phase 2 to Phase 3. Finalisation of dosing optimisation is underway, including investigating MPL in combination either with prednisolone or CHOP-based protocols[1]. The trial involves treatment at home with a consultation at the dog’s nearest trial centre, as listed below. Basic Inclusion and Exclusion criteria are also listed below. Trial centre veterinarians will provide greater detail about enrolment and the nature of the trial.

[1] L- asparaginase, vincristine, cyclophosphamide, prednisolone, and doxorubicin

Download All MPL Trial Centres

Participating MPL Trial Centres in Australia

Dr Sonya Yu
Animal Referral Hospital,
Homebush, Sydney NSW
tel: (02) 9758 8666


Dr Kathleen O’Connell
Animal Referral Hospital,
Sinnamon Park, Brisbane QLD
Tel: (07) 3172 0593


Dr Catherine Chan
Veterinary Specialist Services,
Jindalee, Brisbane, Qld
Tel: 1800 442 648


Dr Sue Bennett
Western Australian Veterinary Emergency and Specialty (WAVES),
Success, Perth WA
Tel: (08) 9412 5700


Dr Jessica Finlay
Perth Veterinary Specialists,
Osborne Park, Perth WA
Tel: (08) 9204 0400


Dr Renee Pigdon
Vets Albury Wodonga – Petfocus Vetcare
Albury NSW
Tel: (02) 6040 9099

Participating MPL Trial Centres in New Zealand

Dr Tommy Fluen and Dr Mike Coleman
Veterinary Specialists  Auckland (VSA)
Sylvia Park Hospital
Corner Hotunui Drive & Te Apunga Place,
Sylvia Park
New Zealand

tel: +64 9-320 5645

Basics of Inclusion Criteria

• Dogs of any sex, at least one year of age, with B cell nodal lymphoma
• No other significant intercurrent disease
• No previous medication for the lymphoma
• WHO stage 1-5, substage a.
• Modified Karnofsky performance score 0 or 1

Basics of Exclusion Criteria

• Dogs that have received prior treatment for lymphoma
• Any corticosteroid use in preceding 8 weeks
• Puppies less than 1 year old
• Lactating or pregnant bitches
• Dogs used for breeding
• Modified Karnofsky performance score 2 or above

MPL Trial Centres

Participating MPL Trial Centres in the USA

Dr Meighan Daly
Heart of Texas Veterinary Specialty Centre

115 E Old Settlers Blvd

Round Rock

TX 78664


tel: +1 512-744-4644

More Information About Trial Participation

Owners will have to transport their dogs to their respective centres and pay the cost of the initial consultation for diagnosis. Once the pet is diagnosed with lymphoma, PharmAust will cover all clinical trial costs, including travel expenses to and from the trial centre as well as post-trial maintenance treatment if both pet owners and vets consider this might be beneficial.

The MPL tablets will be administered at home, and owners will be asked to keep a simple logbook during the trial period.

Pet owners interested in enrolling their dogs in the MPL trial need to contact their veterinarian for a referral to their nearest trial centre.

Veterinarians – for questions about patient referrals or trial sites, please get in touch with Principal Investigator, Dr Kim Agnew at

For questions about the MPL trial program, please get in touch with Dr Roger Aston, Executive Chairman, PharmAust Ltd

Veterinary Trial Testimonials

To read the pet owners’ trial testimonials, visit

One of the dogs on trial (left) going camping with his friend.

[1] L- asparaginase, vincristine, cyclophosphamide, prednisolone, and doxorubicin